Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar.
Author(s): Van Damme K, Behets F, Ravelomanana N, Godornes C, Khan M, Randrianasolo B, Rabenja NL, Lukehart S, Cohen M, Hook E
Affiliation(s): Department of Medicine, Division of Infectious Diseases, University of North Carolina, Madagascar (UNC-MAD), Antananarivo, Madagascar.
Publication date & source: 2009-12, Sex Transm Dis., 36(12):775-6.
Publication type: Clinical Trial, Phase III; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural
Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar.
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