Comparison of effects of quinapril versus enalapril on vasoactive substances following acute myocardial infarction.
Author(s): Tsikouris JP, Simoni J, Suarez JA, Sutthiwan P, Ziska M, Meyerrose GE
Affiliation(s): School of Pharmacy, Texas Tech Univesity Health Sciences Center, Lubbock 79430-9410, USA.
Publication date & source: 2004-09-01, Am J Cardiol., 94(5):641-3, A9.
Publication type: Clinical Trial; Randomized Controlled Trial
The true existence of a class effect in angiotensin-converting enzyme (ACE) inhibitors remains controversial. The present trial explored the effects of 2 ACE inhibitors after acute myocardial infarction and found no difference in endothelin-1 production but a greater increase in the production of total nitric oxide with quinapril than with enalapril. Copyright 2004 Excerpta Medica, Inc.
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