Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: a pilot randomised controlled trial.

Author(s): Tong SY, Andrews RM, Kearns T, Gundjirryirr R, McDonald MI, Currie BJ, Carapetis JR

Affiliation(s): Menzies School of Health Research, Charles Darwin University, Darwin, Australia. steven.tong@menzies.edu.au

Publication date & source: 2010-03, J Paediatr Child Health., 46(3):131-3.

Publication type: Comparative Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

We conducted a pilot randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children. Treatment was successful in 7 of 7 children treated with trimethoprim-sulfamethoxazole and 5 of 6 treated with benzathine penicillin. Trimethoprim-sulfamethoxazole achieved microbiological clearance and healing of sores from which beta-hemolytic streptococci and community-associated methicillin-resistant Staphylococcus aureus were initially cultured.