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A randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of concurrent alcohol use disorder and pathological gambling.

Author(s): Toneatto T, Brands B, Selby P

Affiliation(s): Clinical Research Department, Center for Addiction and Mental Health, Toronto, Ontario, Canada. tony toneatto@camh.net

Publication date & source: 2009-05, Am J Addict., 18(3):219-25.

Publication type: Randomized Controlled Trial; Research Support, Non-U.S. Gov't

The efficacy of naltrexone as a treatment for concurrent alcohol abuse or dependence and pathological gambling was evaluated in a randomized, double-blind, placebo-controlled trial. Fifty-two, mostly male, subjects were recruited from the community and received 11 weeks of medication during which cognitive-behavioral counseling was also provided. No significant group differences were found on any alcohol or gambling variable (ie, frequency, quantity, expenditures) at post-treatment or at the one year follow-up. However, a strong time effect was found suggesting that treatment, in general, was effective. The use of naltrexone to treat concurrent alcohol use and gambling problems was not supported.

Page last updated: 2009-10-20

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