Pharmacokinetics of ambenonium chloride in dogs after intravenous and oral administration.

Author(s): Tharasse-Bloch C, Chabenat C, Boucly P, Boismare F, Marchand J

Affiliation(s): Laboratoire de Pharmacochimie, U.E.R. de Medecine-Pharmacie de Rouen, St. Etienne du Rouvray, France.

Publication date & source: 1989-02, Arzneimittelforschung., 39(2):257-8.

Plasma concentrations of ambenonium chloride (Mytelase) were studied, using a high pressure liquid chromatographic technique, in 11 dogs, after intravenous or oral administration of the drug. The results found suggest a complex multi-compartment storage with several periodical releases in general circulation.