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Methsuximide for intractable childhood seizures.

Author(s): Tennison MB, Greenwood RS, Miles MV

Affiliation(s): Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill 27599-7025.

Publication date & source: 1991-02, Pediatrics., 87(2):186-9.

Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency. No serious or irreversible adverse effects were seen. Methsuximide is frequently overlooked and may be an effective adjunctive antiepileptic for children with intractable seizures.

Page last updated: 2007-05-02

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