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[Randomized controlled trials for the prevention and treatment of glucocorticoid-induced osteoporosis]. [Article in Japanese]

Author(s): Suzuki Y.

Affiliation(s): Tokai University School of Medicine, Department of Internal Medicine, Division of Rheumatology.

Publication date & source: 2006, Clin Calcium. , 16(11):1834-42

The effectiveness of drug therapy for the prevention or treatment of glucocorticoid-induced osteoporosis has been reported. Especially, the beneficial effects of bisphosphonates (etidoronate, alendronate, and risedronate) to prevent bone loss and fractures have been confirmed by the large-scale, multicenter, double-blind, randomized controlled trials in terms of both primary and secondary prevention. This article reviews the results of recent randomized prospective trials using bisphosphonates in glucocorticoid-induced osteoporosis.

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