The efficacy of ANSAID (flurbiprofen) as an analgesic in foot surgery.

Author(s): Soulier SM, Page JC, Larsen LC, Grose BC

Affiliation(s): Upjohn Company: Pharmacia & Upjohn, Kalamazoo, MI, USA.

Publication date & source: 1997-11, J Foot Ankle Surg., 36(6):414-7

Publication type: Clinical Trial; Randomized Controlled Trial

Eighty-three patients scheduled for outpatient surgery were enrolled in this double-blind, randomized trial designed to compare the safety and efficacy of single and multiple doses of flurbiprofen 50 mg. and acetaminophen 300 mg. plus codeine phosphate 30 mg. During the multiple dose segment, statistically significant differences were observed during the first 24 hour postoperative period regarding relief of pain and pain intensity. Flurbiprofen provided greater relief of pain than the acetaminophen with codeine phosphate combination. This study supports the use of flurbiprofen as a suitable alternative to acetaminophen plus codeine phosphate in the treatment of postoperative pain following foot surgery.