Comparative study of diclofenac sodium and flurbiprofen in osteoarthritis.

Author(s): Shaikh KA, Ali M, Sharafatullah T

Affiliation(s): Department of Pharmacology, Dow Medical College, BMSI, Karachi.

Publication date & source: 1996-12, J Pak Med Assoc., 46(12):270-2.

Publication type: Clinical Trial; Comparative Study ; Randomized Controlled Trial

A comparative study was conducted to evaluate the therapeutic efficacy of diclofenac sodium and flurbiprofen both non-steroidal anti-inflammatory drugs (NSAIDS) in osteoarthritis. Forty patients of either sex between the ages of 35-60 years suffering from osteoarthritis of at least one knee joint minimum of eight weeks duration were included in the study. Diclofenac sodium exhibited better results by improving the signs and symptoms of osteoarthritis in both high and low doses compared to flurbiprofen. The adverse effects observed were similar in both groups.