Does the addition of tramadol and ketamine to ropivacaine prolong the axillary
brachial plexus block?
Author(s): Senel AC(1), Ukinc O(1), Timurkaynak A(2).
Affiliation(s): Author information:
(1)Department of Anesthesiology, Medical Faculty of Karadeniz Technical
University, 61080 Trabzon, Turkey. (2)Department of Orthopedics, Medical Faculty
of Karadeniz Technical University, 61080 Trabzon, Turkey.
Publication date & source: 2014, Biomed Res Int. , 2014:686287
BACKGROUND AND OBJECTIVES: A prospective, randomized, controlled, double-blind
clinical trial to assess the effect of tramadol and ketamine, 50 mg, added to
ropivacaine in brachial plexus anesthesia.
METHODS: Thirty-six ASA physical statuses I and II patients, between 18 and 60
years of age, scheduled for forearm and hand surgery under axillary brachial
plexus block, were allocated to 3 groups. Group R received 0.375% ropivacaine in
40 mL, group RT received 0.375% ropivacaine in 40 mL with 50 mg tramadol, and
group RK received 0.375% ropivacaine in 40 mL with 50 mg ketamine for axillary
brachial plexus block. The onset times and the duration of sensory and motor
blocks, duration of analgesia, hemodynamic parameters, and adverse events
(nausea, vomiting, and feeling uncomfortable) were recorded.
RESULTS: The onset time of sensorial block was the fastest in ropivacaine +
tramadol group. Duration of sensorial and motor block was the shortest in the
ropivacaine + tramadol group. Duration of analgesia was significantly longer in
ropivacaine + tramadol group.
CONCLUSION: We conclude that when added to brachial plexus analgesia at a dose of
50 mg, tramadol extends the onset and duration time of the block and improves the
quality of postoperative analgesia without any side effects.
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