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[Evaluation of dipotassium clorazepate in pre-anesthetic medication]

Author(s): Seabra M, Esteves S, Diaz J, Sanmartin D, Araujo MS

Affiliation(s): Servico de Anestesia, Hospital Geral de Santo Antonio, Porto.

Publication date & source: 1991-05, Acta Med Port., 4(3):131-3.

The anxiolytic action of clorazepate 15 mg PO on the eve and 1 hour before the surgical procedure was studied in 50 ASA class 1 patients (18-60 years old, 46-86 kg) scheduled for elective non-oncological surgery. Anxiety, assessed by the anaesthetist employing a modified Hamilton Anxiety Scale, was lower after premedication in 46 patients (p less than 0.01) and only few side-effects were noted. As a conclusion we suggested that clorazepate PO as anaesthetic premedication is suitable for anxiety relief.

Page last updated: 2006-01-31

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