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Drug-induced liver injury caused by the histrelin (Vantus) subcutaneous implant.

Author(s): Ricker JM, Foody WF, Shumway NM, Shaw JC

Affiliation(s): Department of Gastroenterology, Wilford Hall Medical Center, Lackland AFB, TX, USA. doctorntraining2004@yahoo.com

Publication date & source: 2010-01, South Med J., 103(1):84-6.

Publication type: Case Reports

Drug-induced liver injury (DILI) is the leading cause of acute hepatic failure in the United States. Up to 13% of acute liver failure cases occur due to drugs other than acetaminophen. This clinical diagnosis, made after other causes of liver injury have been excluded, requires establishing a causal relationship between drug exposure and liver injury. The case of a patient with liver injury following a subcutaneous histrelin (Vantus) implant as therapy for advanced prostate cancer is presented.

Page last updated: 2010-10-05

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