Therapeutic tricyclic antidepressant drug monitoring in younger and older depressive patients.

Author(s): Radziwon-Zaleska M, Matsumoto H, Skalski M, Wilkowska J, Januszko P, Matoszko D, Dziklinska A, Gmaj B, Szelenberger W

Affiliation(s): Department of Psychiatry, Medical University of Warsaw, Nowowiejska 27, PL 00-665 Warszawa, Poland. maria.radziwon@psych.waw.pl

Publication date & source: 2006-07, Pharmacol Rep., 58(4):501-6.

Publication type: Clinical Trial; Comparative Study

The present study shows the evaluation of clinical state and serum level of tricyclic antidepressants in thirty-eight depressive younger and elderly patients during 8-week observation. We observed no statistically significant differences, neither in psychometric scale scores nor in drug serum levels in both groups of patients.