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[Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts]

Author(s): Quera-Salva MA, Philip P, Taillard J, Letrequeser R, Allain H, Garcia-Acosta S, Kermad I, Krieger J, Dib M

Affiliation(s): Hopital Raymond Poincare, AP-HP, Universite Paris Ouest, Garches.

Publication date & source: 2002-11, Rev Neurol (Paris)., 158(11):1102-6.

Publication type: Clinical Trial; English Abstract; Randomized Controlled Trial

We investigated the effect of adapted management of sleep on the duration and quality of sleep in shift workers working the night shift. Twenty-nine shift workers suffering from insomnia were included and treated with zopiclone (7.5mg/day) or placebo according to a random double-blind protocol. Patients completed a sleep diary and a wrist actigraph was used to evaluate episodes of rest/activity. A self-administered subjective sleep questionnaire was filled out just after awakening. Zopicone was found to increase the duration of sleep significantly (p<0.05) over the baseline duration after the first and second night on duty. Subjective estimation of sleep was better in patients taking zopiclone who exhibited a smaller number of shorter awakening episodes. In conclusion: zopiclone improves the quality and duration of sleep in shift workers suffering from insomnia.

Page last updated: 2007-10-18

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