[Visual evoked potentials in children cured with sodium-calcium versenate because of high blood lead level--the prospective study]

Author(s): Pojda-Wilczek D, Herba E, Schneiberg B

Affiliation(s): Z Katedry i Oddzialu Klinicznego Okulistyki Slaskiej Akademii Medycznej Szpital Specjalistyczny nr 1 w Bytomiu.

Publication date & source: 2005, Klin Oczna., 107(10-12):662-4.

Publication type:

PURPOSE: To find out if blood lead level (Pb-B) changes have influence on visual evoked potentials. MATERIAL AND METHODS: 18 children (36 eyes) treated with CaNa2EDTA because of chronic environmental lead poisoning were examined two times: first at age 2-15.5 (mean 8) years and second 4 years later. For pattern VEP LKC equipment, UTAS E-2000 program and stimulations of 13', 26', 52', 105' were used. P100 amplitude and latency were calculated. RESULTS: Pb-B was decreased from 150-486 (mean 262) microg/l to 42-248 (mean 103) microg/l. After 4 years, P100 latency was significantly delayed in children with Pb-B above 100 microg/l at second examination. In children with Pb-B below 100 microg/l no significant differences between two consecutive examinations were observed. There were no significant differences in P100 amplitude. CONCLUSIONS: Delayed P100 latency of PVEP in children is permanent but non-progressive if Pb-B is lower than 100 microg/l.