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[Double-blind clinical study of the treatment of melasma with azelaic acid versus hydroquinone]

Author(s): Piquero Martin J, Rothe de Arocha J, Beniamini Loker D

Affiliation(s): Instituto de Biomedicina, Caracas, Venezuela.

Publication date & source: 1988, Med Cutan Ibero Lat Am., 16(6):511-4.

Publication type: Clinical Trial; Controlled Clinical Trial

A comparative double-blind study was carried out on sixty patients received oral contraceptives. Patients were treated with 20% azelaic acid or 4% hydroquinone. They were observed for 24 weeks and the results compared and checked for side effects. The results showed that the azelaic acid was not better than the hydroquinone in the treatment of melasma but it could be used as alternative drug.

Page last updated: 2006-01-31

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