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Efficacy of a novel internal dry period teat sealant containing 0.5% chlorhexidine against experimental challenge with Streptococcus uberis in dairy cattle.

Author(s): Petrovski KR, Caicedo-Caldas A, Williamson NB, Lopez-Villalobos N, Grinberg A, Parkinson TJ, Tucker IG

Affiliation(s): Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand. k.r.petrovski@massey.ac.nz

Publication date & source: 2011-07, J Dairy Sci., 94(7):3366-75.

Publication type: Randomized Controlled Trial; Research Support, Non-U.S. Gov't

The incidence of clinical mastitis and infection status at calving was assessed in quarters treated with 1 of 2 internal teat sealants at the time of dry off. Two contralateral quarters per cow (n=63 cows) were treated with a sealant that contained 0.5% chlorhexidine; the other quarters were treated with a commercial teat sealant. Ten cows were untreated (controls). On d 2, 4, and 16 after dry off, cows were challenged with Streptococcus uberis S210 strain. Cows were examined daily for 34 d after drying off and cases of clinical mastitis were recorded. Milk samples were collected for culture from any quarters that developed clinical mastitis during the first 34 d after drying-off and from all quarters on d -5 and 0 relative to treatment and at the first and twentieth milking after calving. The incidence of clinical mastitis during the examination period was lower in treated quarters (n=7/252; 1.5%; lower incidence for those treated with chlorhexidine-containing teat sealant n=3/126; 1.2%) than in untreated quarters (n=13/40; 26.8%). The protection against intramammary infection after calving, adjusted for the effect of cow, was higher in quarters treated with the novel teat sealant (89/105; 15.2%; 95% CI=9.6-23.4) than in those treated with the commercial teat sealant (71/104; 31.7%; 95% CI=23.5-41.3) and untreated controls (6/28; 78.6%; 95% CI=59.8-90.0), respectively. Quarters treated with teat sealants were less likely to have an intramammary infection after calving and had a lower incidence of clinical mastitis during the early dry period than did untreated controls in this challenge study. Copyright (c) 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Page last updated: 2011-12-09

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