Successful salvage therapy with inhaled zanamivir in a patient with peramivir-resistant pandemic influenza A (H1N1) 2009 virus.
Author(s): Park KH, Lee SO, Choi SH, Kim MN, Lee JH, Yi H, Kim MS, Hong EH, Kim YS, Woo JH, Kim SH
Affiliation(s): Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Publication date & source: 2011-02, Scand J Infect Dis., 43(2):151-5. Epub 2010 Sep 21.
Publication type: Case Reports
We describe a patient with multiple myeloma who developed a pandemic influenza A (H1N1) 2009 virus infection during chemotherapy. The clinical condition of the patient worsened and viral shedding persisted despite 10 days of peramivir treatment; however viral shedding ceased and the patient recovered completely with inhaled zanamivir.
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