Effect of losartan versus atenolol on aortic valve sclerosis (a LIFE substudy).

Author(s): Olsen MH, Wachtell K, Bella JN, Liu JE, Boman K, Gerdts E, Papademetriou V, Nieminen MS, Rokkedal J, Dahlof B, Devereux RB

Affiliation(s): Glostrup University Hospital, Glostrup, Denmark. mho@dadlnet.dk

Publication date & source: 2004-10-15, Am J Cardiol., 94(8):1076-80.

Publication type: Clinical Trial; Randomized Controlled Trial

Neither losartan- nor atenolol-based antihypertensive regimens could prevent the progression of aortic valve (AV) sclerosis in elderly, high-risk hypertensive patients, and the regression of AV sclerosis did not translate into reduced cardiovascular risk.