DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Prevalence of pin tract infection: the role of combined silver sulphadiazine and chlorhexidine dressing.

Author(s): Ogbemudia AO, Bafor A, Edomwonyi E, Enemudo R

Affiliation(s): Department of Surgery, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria. alfredoghogho@yahoo.com

Publication date & source: 2010-09, Niger J Clin Pract., 13(3):268-71.

Publication type: Comparative Study; Randomized Controlled Trial

OBJECTIVE: Infection at the pin tract is a common complication of external fixation. This study was done to compare the rate of pin site infection following combined 1% silver sulphadiazine and 5 % chlorbexidine dressing with 5% chlorhexidine dressing alone. METHOD: This was a prospective controlled study which compared the results of pin site dressing using a combination of chlorhexidine and silver sulphadiazine cream (Study group) with dressing using chlorhexidine alone. Eligible patients had external fixation in the treatment of open fractures or orthopaedic conditions. Pin-tract infection was deemed to be present iferythema, cellulitis or purulent discharge occurred around a pin site. We did not distinguish between deep and superficial infection. RESULTS: The study group had one hundred and seventy pin sites while the control group had one hundred and sixty-four pin sites. Thirty-eight patients, in whom thirty-seven uniplanar external fixators and one Ilizarov ring fixator were used, made up both groups. Three patients (7.9%) had pin tract infection in the study group while nine patients (23.7%) had pin tract infection in the control group. CONCLUSION: There was a significantly lower prevalence of pin-tract infection amongst patients whose external fixation pins were dressed with 1% silver sulphadiazine and 5% chlorhexidine than in those dressed with chlorhexidine alone (P = 0.03). Therefore, we advocate the use of a combination of silver sulphadiazine and chlorhexidine for pin site dressing.

Page last updated: 2011-12-09

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017