Oral enalapril-hydrochlorothiazide-methyldopa as first line treatment for severe hypertension in Nigerians.

Author(s): Ofor OO

Affiliation(s): Medical Unit, Royal Victoria Hospital, Banjul, The Gambia. okezieofor@hotmail.com

Publication date & source: 2004-01, Trop Doct., 34(1):32-3.

A combination of low-dose oral enalapril, methyldopa and hydrochlorothiazide was evaluated in the acute treatment of severe hypertension. Blood pressure moved from an average 210/120 mmHg at the onset to an average 135/79 mmHg within 24 hours, without any significant side effects and at about half the cost of commonly used parenteral hydralazine.