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Oral mucous membrane pemphigoid in a 6-year-old boy: diagnosis, treatment and 4 years follow-up.

Author(s): Mostafa MI, Hassib NF, Nemat AH

Affiliation(s): Human Genetics and Genome Research Division, Department of Oro-dental Genetics. mostafanrc@yahoo.com

Publication date & source: 2010-01, Int J Paediatr Dent., 20(1):76-9.

Publication type: Case Reports; Research Support, Non-U.S. Gov't

BACKGROUND: Childhood oral pemphigoid is extremely rare and usually takes the form of desquamative gingivitis. CASE REPORT: We describe a 6-year-old boy who presented with gingival bleeding, pain, eating difficulty, and peeling of the gums. Clinical examination revealed desquamative gingivitis with no extra-oral involvement. The diagnosis was established as oral pemphigoid based on the clinical, histological, and immunofluorescence findings. Symptoms resolved on treatment with occlusive topical corticosteroids. The patient was a carrier of the HLA-DQB(1)*0301 allele. CONCLUSION: Mucous membrane pemphigoid should be considered in the differential diagnosis of chronic desquamative gingivitis in childhood. Occlusive therapy with topical fluocinonide may alleviate the symptoms.

Page last updated: 2010-10-05

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