Rational approaches to the treatment of patients with interstitial cystitis.

Author(s): Moldwin RM, Evans RJ, Stanford EJ, Rosenberg MT

Affiliation(s): Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA. rmoldwin@aol.com

Publication date & source: 2007-04, Urology., 69(4 Suppl):73-81.

Publication type: Review

Symptoms of interstitial cystitis can usually be successfully managed with heparinoid therapy to theoretically alter bladder urothelial abnormalities, and with oral medications to inhibit neural upregulation or to control mast cell dysfunction. Other forms of care ranging from intravesical therapy to endoscopic, percutaneous, or open surgery are options that may be used singly or in combination to optimize symptom reduction.