A comparative study of pipemidic acid and nitrofurantoin in the treatment of uncomplicated urinary tract infections.

Author(s): Meyer EC, Schoeman HS

Affiliation(s): Department of Pharmacology, University of Pretoria.

Publication date & source: 1987-11-21, S Afr Med J., 72(10):663-5.

Publication type: Clinical Trial; Comparative Study ; Randomized Controlled Trial

In an open uncontrolled trial 60 women with confirmed uncomplicated urinary tract infections were randomly allocated to receive either pipemidic acid (Septidron; Ethimed) or nitrofurantoin for 10 days. Urine cultures were done on day 1 and day 10. No statistical difference was found in the subjective and objective assessments of the response to the two medications and it is concluded that pipemidic acid is a satisfactory and effective alternative to nitrofurantoin in the treatment of uncomplicated urinary tract infections in women.