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The effects of clomipramine hydrochloride in cats with psychogenic alopecia: a prospective study.

Author(s): Mertens PA, Torres S, Jessen C

Affiliation(s): Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.

Publication date & source: 2006-09, J Am Anim Hosp Assoc., 42(5):336-43.

Publication type: Research Support, Non-U.S. Gov't

A double-blind, placebo-controlled clinical trial was conducted to determine the efficacy of clomipramine hydrochloride in cats with psychogenic alopecia. Twenty-five cats were randomly assigned to receive clomipramine hydrochloride (0.5 mg/kg orally q 24 hours) or placebo for 56 days. Eleven cats in each group completed the trial. The results of this study showed that clomipramine hydrochloride failed to demonstrate significant changes in the number of grooming bouts, hair regrowth, and the area of alopecia in cats with psychogenic alopecia when compared to a placebo. It was uncertain whether these results reflected a lack of drug efficacy, insufficient treatment duration, or an insufficient number of cases enrolled.

Page last updated: 2007-02-12

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