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Low-dose oral tri-iodothyronine does not directly increase food intake in man.

Author(s): Martin NM, Small CJ, Lee JL, Ellis S, Dhillo WS, Smith KL, Kong WM, Frost GS, Bloom SR

Affiliation(s): Department of Metabolic Medicine, Hammersmith Hospital, Imperial College London, London, UK.

Publication date & source: 2007-05, Diabetes Obes Metab., 9(3):435-7.

Publication type: Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Previously, we have shown that low-dose tri-iodothyronine (T3) increases food intake in rodents. This randomised, double-blind, placebo-controlled study aimed to investigate the effects of low-dose T3 on food intake in normal body weight individuals. However, despite an elevation in fT3 comparable to our earlier studies, administration of low-dose T3 in the fasted state did not stimulate food intake in man.

Page last updated: 2007-08-04

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