Cholinergic toxicity resulting from ocular instillation of echothiophate iodide eye drops.

Author(s): Manoguerra A, Whitney C, Clark RF, Anderson B, Turchen S

Affiliation(s): San Diego Regional Poison Center, UCSD Medical Center 92103-8925, USA.

Publication date & source: 1995, J Toxicol Clin Toxicol., 33(5):463-5.

Publication type: Case Reports

A patient developed a severe cholinergic syndrome from the use of echothiophate iodide ophthalmic drops, presented with profound muscle weakness and was initially given the diagnosis of myasthenia gravis. Red blood cell and serum cholinesterase levels were severely depressed and symptoms resolved spontaneously following discontinuation of the eye drops.