Splenic abscess in a patient with type 3 Gaucher's disease receiving enzyme replacement therapy.

Author(s): Maclean K, Wilson MJ

Affiliation(s): Departments of Paediatrics and Clinical Genetics, Royal Alexandra Hospital for Children, Sydney, New South Wales, Australia.

Publication date & source: 1999-02, J Pediatr., 134(2):245-7.

Publication type: Case Reports; Research Support, Non-U.S. Gov't

We report the rare complication of a splenic abscess in an 11-year-old girl with type 3 Gaucher's disease, massive splenomegaly, and a splenic cyst after commencement of enzyme replacement therapy. This case highlights potential difficulties in establishing the diagnosis of splenic abscess in the presence of pre-existing splenic pathology.