A randomized, double-blind study examining the comparative efficacies and safety of inhaled epinephrine and nasal decongestant in hospitalized infants with acute bronchiolitis.
Author(s): Livni G, Rachmel A, Marom D, Yaari A, Tirosh N, Ashkenazi S
Affiliation(s): Department of Pediatrics A, Schneider Children's Medical Center, Petach Tikva 49202, Israel.
Publication date & source: 2010-01, Pediatr Infect Dis J., 29(1):71-3.
Publication type: Comparative Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Optimal treatment of acute bronchiolitis is currently unclear. In a double-blind study, we found no significant differences between inhaled epinephrine and nasal decongestant in hospitalized infants with acute bronchiolitis regarding length of hospitalization, need for oxygen supplementation, or intravenous fluids and clinical score. Nasal decongestant is as effective as inhaled epinephrine in acute bronchiolitis.
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