Potentiating effect of fluphenazine decanoate and risperidone on development of neuroleptic malignant syndrome.
Author(s): Liu PY, Wu PC, Chen CY, Chen YC
Affiliation(s): Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Publication date & source: 2011-01, Gen Hosp Psychiatry., 33(1):84.e5-7. Epub 2010 Dec 23.
Publication type: Case Reports; Research Support, Non-U.S. Gov't
We present the case of a woman with paranoid schizophrenia who was receiving oral risperidone. She developed neuroleptic malignant syndrome (NMS) following the addition of depot fluphenazine for the treatment of refractory delusions. NMS subsided and psychotic features were controlled after both antipsychotics were discontinued and the patient was treated instead with olanzapine. Crown Copyright (c) 2011. Published by Elsevier Inc. All rights reserved.
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