Grinspan's syndrome: a drug-induced phenomenon?

Author(s): Lamey PJ, Gibson J, Barclay SC, Miller S

Affiliation(s): Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.

Publication date & source: 1990-08, Oral Surg Oral Med Oral Pathol., 70(2):184-5.

Publication type: Case Reports

Three cases of apparently drug-induced Grinspan's syndrome involving the triad of oral lichen planus, diabetes mellitus, and hypertension are reported. Because drug therapy for diabetes mellitus and hypertension is capable of producing lichenoid reactions of the oral mucosa, the question arises as to whether Grinspan's syndrome is an iatrogenically induced syndrome.