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Terazosine and tamsulosin in non bacterial prostatitis: a randomized placebo-controlled study.

Author(s): Lacquaniti S, Destito A, Servello C, Candidi MO, Weir JM, Brisinda G, Alcini E

Affiliation(s): Department of Urology, Catholic University of S. Cuore, Rome, Italy. s.lacquaniti@usa.net

Publication date & source: 1999-12, Arch Ital Urol Androl., 71(5):283-5.

Publication type: Clinical Trial; Randomized Controlled Trial

Eighteen patients with inflammatory process of the prostate met criteria for the inclusion in the study: 1) non bacterial prostatitis; 2) no previous treatment. Then they were randomized into three groups as it follows: terazosine, tamsulosin and placebo. Alpha-blockers and placebo were given for two months, after which further uroflowmetry was performed. Symptom score was evaluated before and after treatment. Terazosine was effective in reducing TO (p = 0.01) as tamsulosin and placebo did not. Both terazosine (p = 0.034) and tamsulosin (p = 0.006) reduced max TQ as placebo did not. Symptom score significantly improved in patients receiving terazosine (p = 0.0002) and tamsulosin (p = 0.001) while insignificantly in whose receiving placebo.

Page last updated: 2006-01-31

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