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Forensic toxicological implication of an autopsy case of mixed drug overdose involving clomipramine, chlorpromazine and flunitrazepam.

Author(s): Kinoshita H, Nishiguchi M, Kasuda S, Takahashi M, Ouchi H, Minami T, Matsui K, Yamamura T, Motomura H, Ohtsu N, Yoshida S, Adachi N, Ohta T, Komeda M, Ameno K, Hishida S

Affiliation(s): Department of Legal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. kinochin@hyo-med.ac.jp

Publication date & source: 2008-07, Soud Lek., 53(3):28-30.

Publication type: Case Reports

A case of fatal poisoning involving clomipramine, chlorpromazine and flunitrazepam is presented. Quantitative toxicological analysis showed that the concentrations of clomipramine, chlorpromazine and 7-aminoflunitrazepam (a metabolite of flunitrazepam) in the femoral blood were 3.24 microg/ml, 0.36 Kg/ml and 0.61 microg/ml, respectively, and large amounts of drugs were also detected from the stomach contents. We concluded that the cause of death was due to the combined use of clomipramine, chlorpromazine and flunitrazepam.

Page last updated: 2008-11-03

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