Ichthyosis follicularis, alopecia and photophobia (IFAP) syndrome treated with acitretin.

Author(s): Khandpur S, Bhat R, Ramam M

Affiliation(s): Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi 110029, India. shaifalikhandpur@eth.net

Publication date & source: 2005-11, J Eur Acad Dermatol Venereol., 19(6):759-62.

Publication type: Case Reports

We describe a 3-year-old male patient with the ichthyosis follicularis, alopecia and photophobia (IFAP) syndrome, who developed cutaneous and ocular involvement in infancy. In addition, he had growth retardation and borderline intelligence; no other systemic involvement was found on detailed investigation. A moderate response to acitretin therapy (1 mg/kg) administered for 6 months was observed, with improvement in cutaneous features and corneal erosions and no change in alopecia or photophobia.