Topical anesthetic (lidocaine-prilocaine) cream application before speculum
examination in postmenopausal women.
Author(s): Keskin AE, Onaran Y, Duvan IC, Simavli S, Kafali H.
Affiliation(s): Department of Obstetrics and Gynecology, Fatih University Medical School, Ankara,
Turkey. eakeskin@hotmail.com
Publication date & source: 2012, J Minim Invasive Gynecol. , 19(3):350-5
STUDY OBJECTIVE: To evaluate the effectiveness of lidocaine-prilocaine (EMLA 5%)
cream application to genital mucosa for reducing pain or discomfort associated
with speculum examination in postmenopausal women.
DESIGN: A randomized controlled study (Canadian Task Force classification I).
SETTING: A university hospital.
PATIENTS: One-hundred thirty-four postmenopausal women.
INTERVENTIONS: The subjects were randomized to an EMLA cream group, a lubricant
gel group, or a control group. General data was collected, including age, body
weight, gravidity, parity, smoking habits, history of diabetes mellitus, previous
gynecologic operations, dyspareunia, sexual activity, and duration of menopause.
All patients were asked to score pain at 3 time points (insertion, dilation, and
extraction of speculum) during the procedure using a visual analog scale. Pain
intensity during speculum examination was compared between the groups.
MEASUREMENTS AND MAIN RESULTS: There was no statistically significant difference
between the EMLA cream, the lubricant gel, and the control groups in terms of
age, weight, gravidity, parity, dyspareunia, duration of menopause, sexual
activity, smoking habit, diabetes mellitus, previous vaginal and other
gynecological procedures, vaginal length, and serum follicle-stimulating hormone
and estradiol levels (p > .05). The pain scores obtained during all phases of
speculum application were significantly lower in the EMLA group than in both the
lubricant gel and the control groups (p < .001). Comparing the gel and the
control groups, a lower pain score was observed in the former, except for the
second phase of the examination (p < .001).
CONCLUSION: Topical application of EMLA 5% cream on genital mucosa of
postmenopausal women before vaginal examination significantly reduces pain
associated with speculum application.
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