Metaphyseal undertubulation in gaucher disease: resolution at MRI in a patient undergoing enzyme replacement therapy.

Author(s): Kelman CG, Disler DG

Affiliation(s): Department of Radiology, Albany Medical College, NY, USA.

Publication date & source: 2000-01, J Comput Assist Tomogr., 24(1):173-5.

Publication type: Case Reports

Gaucher disease is a sphingolipid storage disorder that results in the accumulation of Gaucher cells within the reticuloendothelial system. The life span can be near normal in the most common form. Our case illustrates the resolution of the skeletal findings in Gaucher disease following enzyme replacement therapy. We also report the correlation of these findings with clinical improvement.