Effect of topical cyclosporine on tear functions in tear-deficient dry eyes.

Author(s): Jain AK, Sukhija J, Dwedi S, Sood A

Affiliation(s): Cornea and External Diseases Section, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India. aronkjain@yahoo.com

Publication date & source: 2007-03, Ann Ophthalmol (Skokie)., 39(1):19-25.

Publication type: Comparative Study; Randomized Controlled Trial

We evaluated the efficacy of topical 2% cyclosporine drops in the treatment of tear-deficient dry eye because of acquired primary lachrymal disease (APLD; 15 patients) and Sjogren syndrome (SS; 15 patients). Symptoms of dryness tended to improve in patients with SS. Schirmer score improved in patients with APLD. Topical CsA 2% drops appears to be safe and effective in the treatment of dry eye patients because in patients with APLD and SS, there is trend toward improvement.