Superficial dermabrasion versus topical tretinoin on early striae distensae: a
randomized, pilot study.
Author(s): Hexsel D(1), Soirefmann M, Porto MD, Schilling-Souza J, Siega C, Dal'Forno T.
Affiliation(s): Author information:
(1)Brazilian Center for Studies in Dermatology, Porto Alegre, RS, Brazil; Pontificia
Universidade Catolica do Rio Grande Sul, Porto Alegre, RS, Brazil.
Publication date & source: 2014, Dermatol Surg. , 40(5):537-44
BACKGROUND: Striae distensae (SD) is a common skin condition, with a prevalence
ranging from 40% to 90%, depending on the population studied.
OBJECTIVES: To evaluate the efficacy of superficial dermabrasion and compare it
with that of topical tretinoin cream in the treatment of narrow and early SD.
MATERIALS AND METHODS: Prospective, single-center, randomized, open-label study.
Thirty-two women presenting with early, untreated SD (striae rubra) were included
in this study. One group received 16 weekly sessions of superficial and localized
dermabrasion, and the other used 0.05% tretinoin cream daily. Striae width and
length were measured and compared between groups and over time. Global Aesthetic
Improvement Scale scores and subject satisfaction were also assessed. Biopsies
were performed for subjects who agreed to undergo this procedure, followed by
histologic analyses of the skin samples.
RESULTS: Both treatments were efficacious, with significant improvement in early
SD from baseline, but there was no significant difference between the two
treatments. Histologic assessment showed improvement in epidermal and dermal
layers for the dermabrasion treatment group.
CONCLUSION: Both treatments had similar efficacy, but superficial dermabrasion
had a lower frequency of side effects and better adherence of the patients.
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