Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia.

Author(s): Hassani M, Sahraian MA

Affiliation(s): Tehran University of Medical Sciences, Hassan Abad Square, Sina Hospital, Tehran, Iran. msahrai@sina.tums.ac.ir

Publication date & source: 2006-06, Middle East J Anesthesiol., 18(5):929-31.

Publication type: Randomized Controlled Trial

Succinylcholine is used during induction of anesthesia, and it may induce fasciculations. In this study we demonstrated that intravenous diazepam (1 mg/kg) or lidocaine (1.5 mg/kg) can decrease fasciculations induced by succinylcholine. There is no significant difference between these two drugs in reducing fasciculations moreover, these drugs can also prevent raised blood pressure and heart rate during intubation.