Enzymatic therapy in patients with chronic pancreatitis.

Author(s): Greenberger NJ

Affiliation(s): Department of Medicine, University of Kansas Medical Center, Kansas City, USA.

Publication date & source: 1999-09, Gastroenterol Clin North Am., 28(3):687-93.

Publication type: Review

Pancreatic enzyme replacement therapy has proved useful in the treatment of malabsorption and persistent pain in patients with chronic pancreatitis. The formulation of pancreatic enzyme preparation varies considerably. Treatment of chronic pain is facilitated by the use of a high-protease enzyme preparation, preferably non-microsphere encoated. Treatment of steatorrhea is optimized by use of high-lipase-containing preparations.