A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child.

Author(s): Goto T, Kimura H, Numazaki K, Akiyama M, Kato M, Noda M, Nozaki Y, Tanaka-Taya K, Taniguchi K, Yamagata T, Nishio O, Oogane T, Momoi MY, Okabe N

Affiliation(s): Department of Pediatrics, Jichi Medical School, Yakushiji, Shimotsuke, Japan.

Publication date & source: 2007, Scand J Infect Dis., 39(11-12):1067-70. Epub 2007 Jun 28.

Publication type: Case Reports

We report the case of a 2-y, 11-month-old boy with G1P[8] rotavirus infection accompanied by acute meningoencephalitis. Substitutions in both the VP4 and VP7 genes were found in the identified strain. A commonly circulating G1P[8] rotavirus with such mutations might be associated with the pathogenesis of CNS complications, including meningoencephalitis.