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Hormonal responses to resistance exercise after ingestion of carnosine and anserine.

Author(s): Goto K, Maemura H, Takamatsu K, Ishii N

Affiliation(s): Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan. kgoto@aoni.waseda.jp

Publication date & source: 2011-02, J Strength Cond Res., 25(2):398-405.

Publication type: Comparative Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Intramuscular carnosine buffers protons (H+) in skeletal muscle. We examined the effects of supplementation with chicken breast meat extract (CBEX) containing carnosine and anserine on hormonal responses to resistance exercise. Twenty-two men were assigned to a CBEX drink group (CBEX containing total 2 g of carnosine and anserine) (n = 14) or a placebo drink group (n = 8). The subjects ingested the prescribed drink (100 mL) twice daily for 30 days without physical training. Before and after the supplementation period, the subjects completed 5 sets of bilateral knee extension exercises (with a 90-s rest between sets). The magnitude of the increase in exercise-induced free testosterone did not change significantly after supplementation in either group. The blood lactate response to exercise was attenuated after supplementation in both groups (p < 0.05). In the CBEX group, the plasma epinephrine and norepinephrine concentrations after exercise were significantly lower after supplementation (p < 0.05). The serum growth hormone response to exercise was also reduced in the CBEX group after supplementation (delta value: 5.4 +/- 1.9 ng/mL [pre] vs. 1.6 +/- 0.5 ng/mL [post], p = 0.05). No significant differences in exercise-induced strength reduction (fatigue index) were observed in the 2 groups after supplementation. These results suggest that short-term supplementation with CBEX attenuates the exercise-induced epinephrine, norepinephrine, and growth hormone responses.

Page last updated: 2011-12-09

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