A review of the role of tricyclic medications in the treatment of fibromyalgia syndrome.

Author(s): Goldenberg DL

Affiliation(s): Rheumatology Section, Newton-Wellesley Hospital, MA 02162.

Publication date & source: 1989-11, J Rheumatol Suppl., 19:137-9.

Publication type: Clinical Trial; Review

The rationale behind the use of tricyclic medications in the treatment of fibromyalgia is reviewed. Controlled therapeutic trials have demonstrated significant improvement with these agents. However, important and sustained clinical improvement occurs in the minority of patients.