Efficacy and safety of indomethacin 0.1% versus flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty. The Belgian Study Group on Glaucoma.

Author(s): Goethals M, Missotten L

Affiliation(s): Ophthalmic Clinic, University Hospital St. Raphael, Leuven, Belgium.

Publication date & source: 1994, Doc Ophthalmol., 85(3):287-93.

Publication type: Clinical Trial; Comparative Study ; Multicenter Study; Randomized Controlled Trial

After Argon Laser Trabeculoplasty (ALT), non steroidal anti-inflammatory drugs (Indomethacin 1% suspension and Flurbiprofen 0.03% solution) were shown to be efficient in the management of post laser inflammation. To evaluate the efficacy and safety of Indomethacin 0.1% solution versus Flurbiprofen 0.03% eyedrops in that purpose. 64 patients suffering from glaucoma were recruited in a multicenter randomized double masked study. The results demonstrate that Indomethacin 0.1% eyedrops is as efficient as Flurbiprofen 0.03% in terms of control of post ALT inflammation, with a good tolerance.