[Clinical and bacteriology observation on intraoperation usage of tarivid otic solution in treatment of chronic otitis media with cholesteatoma]

Author(s): Gao Q, Liu Z, Cui Y

Affiliation(s): Department of Otolaryngology, Tongji Hospital, Tongji Medical University, Wuhan 430030.

Publication date & source: 1999-05, Lin Chuang Er Bi Yan Hou Ke Za Zhi., 13(5):219-20.

Publication type:

OBJECTIVE: To determine the effect and safety of Tarivid (oflorxacin) otic solution used during the operation in treatment for chronic otitis media with cholesteatoma. METHOD: 42 patients were divided into two groups. In Tarivid group, 23 patients' operative cavities were soaked with 0.3% Tarivid, while other 19 patients' operative cavities in boric acid group were soaked with 4% boric acid during the open mastoidectomy with tympanoplasty. RESULT: The recovery rate was 82.6% and 50% respectively. There was significant difference between two groups (P < 0.05). No side effect was observed. CONCLUSION: It shows that using Tarivid otic solution in the operation can improve the outcome of the operation and has high security.