Heparin- induced thrombocytopenia occurring in the first trimester of pregnancy: successful treatment with lepirudin. A case report.

Author(s): Furlan A, Vianello F, Clementi M, Prandoni P

Affiliation(s): University of Padua Medical School, Padova, Italy.

Publication date & source: 2006-08, Haematologica., 91(8 Suppl):ECR40.

Publication type: Case Reports

The management of heparin-induced thrombocytopenia (HIT) in pregnancy represents a medical challenge. The advent of new antithrombotic agents that do not cross-react with platelet factor 4 and heparin antibodies represents an important progress, and they are of utmost interest in special situations such as early pregnancy, a situation where the teratogenicity of warfarin precludes its use.