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A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder.

Author(s): Frank JB, Kosten TR, Giller EL Jr, Dan E

Affiliation(s): Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.

Publication date & source: 1988-10, Am J Psychiatry., 145(10):1289-91.

Publication type: Clinical Trial; Comparative Study ; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.

In a double-blind, randomized clinical trial, the efficacy of imipramine and of phenelzine was compared with that of placebo in 34 male veterans with posttraumatic stress disorder (PTSD). Both medications reduced PTSD symptoms.

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