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Detection of massive transplacental haemorrhage by flow cytometry.

Author(s): Fong EA, Davies JI, Grey DE, Reid PJ, Erber WN

Affiliation(s): Haematology, Western Australian Centre for Pathology and Medical Research, Nedlands WA, Australia.

Publication date & source: 2000-12, Clin Lab Haematol., 22(6):325-7.

Publication type: Case Reports

Flow cytometry has been shown to be a more accurate and sensitive method than the Kleihauer-Betke test for the measurement of feto-maternal haemorrhage in Rh(D) incompatibility. This report describes the successful use of flow cytometry to detect and monitor the management of a massive transplacental haemorrhage (105 ml) of fetal Rh(D) positive cells in a Rh(D) negative woman. The report highlights the accuracy and reproducibility of the test and the stability of a blood sample when transferred 596 kilometres to a central testing facility.

Page last updated: 2006-01-31

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