[Combined pharmacological-surgical treatment in exudative age-related macular degeneration].

Author(s): Figurska M, Robaszkiewicz J, Bogdan-Bandurska A

Affiliation(s): Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie. malgorzata-figurska@wp.pl

Publication date & source: 2011, Klin Oczna., 113(1-3):56-9.

Publication type: Case Reports; English Abstract

PURPOSE: The aim of this paper is to present the early phase of treating exudative age-releted macular degeneration (AMD)--coexisting witch vitreoretinal pathology--with combined pharmacological-surgical therapy. MATERIAL AND METHODS: Our observation is based on one clinical case of combined therapy: pars planavitrectomy (PPV) and one intravitrealranibizumab injection. Observation is being carried on larger patient group according to the treatment scheme presented In this paper. RESUTS: In this case described combined pharmacological-surgical therapy allowed a significant improvement in visual acuity and closure of choroidal neovascularization (CNV), leakage confirmed by fluorescein angiography (FA) and optical coherence tomography (AMD). The treatment is being continued--another ranibizumab injection according to PRONTO study reinjection criteria. CONCLUSIONS: The pathomechanism of exudative AMD and coexistance of vitreoretinal pathology implications confirm reasonability of combined therapy.Due to actual clinical studies: the pharmacological -surgical treatment reduces the number of required intravitreal anti-VEGF agents injections. To confirm this observation we need to perform large randomised clinical studies.