Posaconazole treatment for Apophysomyces elegans rhino-orbital zygomycosis following trauma for a male with well-controlled diabetes.

Author(s): Ferguson TD, Schniederjan SD, Dionne-Odom J, Brandt ME, Rinaldi MG, Nolte FS, Langston A, Zimmer SM

Affiliation(s): Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Publication date & source: 2007-05, J Clin Microbiol., 45(5):1648-51. Epub 2007 Mar 7.

Publication type: Case Reports

We report a case of rhino-orbital zygomycosis in a 43-year-old male with well-controlled diabetes mellitus. The patient initially received liposomal amphotericin B, but the infection continued to progress, so posaconazole treatment was begun and eventually led to the cure of his infection. The causative agent was identified as Apophysomyces elegans, an emerging cause of zygomycosis in immunocompetent hosts.